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A deficiency in copper is a well-known cause of premature greying

The duration effect suggests GHK-Cu induces cumulative structural changes in dermal architecture where longer treatment allows more complete remodeling supporting ongoing enhanced function without continuous peptide presence

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Vitamin B 6 , folate, and vitamin B 12 regulate blood levels of homocysteine (see Homocysteine metabolism and Figure 1 above) an amino acid derived from methionine that may be associated with cognitive decline (155)